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BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation

While BTG2 plays an important role in cellular differentiation and cancer, its precise molecular function remains unclear. BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. Our previous experiments revealed that expression of BTG2 promoted mRNA poly...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Stupfler, Benjamin, Birck, Catherine, Séraphin, Bertrand, Mauxion, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773420/
https://ncbi.nlm.nih.gov/pubmed/26912148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10811
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