Therapeutic potential of targeting microRNA‐10b in established intracranial glioblastoma: first steps toward the clinic

MicroRNA‐10b (miR‐10b) is a unique oncogenic miRNA that is highly expressed in all GBM subtypes, while absent in normal neuroglial cells of the brain. miR‐10b inhibition strongly impairs proliferation and survival of cultured glioma cells, including glioma‐initiating stem‐like cells (GSC). Although...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Mol Med
Prif Awduron: Teplyuk, Nadiya M, Uhlmann, Erik J, Gabriely, Galina, Volfovsky, Natalia, Wang, Yang, Teng, Jian, Karmali, Priya, Marcusson, Eric, Peter, Merlene, Mohan, Athul, Kraytsberg, Yevgenya, Cialic, Ron, Chiocca, E Antonio, Godlewski, Jakub, Tannous, Bakhos, Krichevsky, Anna M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772951/
https://ncbi.nlm.nih.gov/pubmed/26881967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505495
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