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Deletion of the Intestinal Plasma Membrane Calcium Pump, Isoform 1, Atp2b1, in Mice is Associated with Decreased Bone Mineral Density and Impaired Responsiveness to 1, 25-Dihydroxyvitamin D(3)

The physiological importance of the intestinal plasma membrane calcium pump, isoform 1, (Pmca1, Atp2b1), in calcium absorption and homeostasis has not been previously demonstrated in vivo. Since global germ-line deletion of the Pmca1 in mice is associated with embryonic lethality, we selectively del...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Ryan, Zachary C., Craig, Theodore A., Filoteo, Adelaida G., Westendorf, Jennifer J., Cartwright, Elizabeth J., Neyses, Ludwig, Strehler, Emanuel E., Kumar, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772868/
https://ncbi.nlm.nih.gov/pubmed/26392310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.09.087
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