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Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-containing Conditioning and Autologous Transplantation for Lymphoma

Cyclophosphamide (Cy) is a prodrug that depends on bioactivation by hepatic cytochrome P450 (CYP) enzymes for its cytotoxicity. We evaluated the influence of single nucleotide polymorphisms (SNPs) of CYP enzymes on the efficacy of autologous hematopoietic cell transplantation (HCT) for lymphoma. SNP...

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Bibliografski detalji
Izdano u:Biol Blood Marrow Transplant
Glavni autori: Bachanova, Veronika, Shanley, Ryan, Malik, Farhana, Chauhan, Lata, Lamba, Vishal, Weisdorf, Daniel J., Burns, Linda J., Lamba, Jatinder Kaur
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772424/
https://ncbi.nlm.nih.gov/pubmed/25677220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.02.001
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