Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-containing Conditioning and Autologous Transplantation for Lymphoma

Cyclophosphamide (Cy) is a prodrug that depends on bioactivation by hepatic cytochrome P450 (CYP) enzymes for its cytotoxicity. We evaluated the influence of single nucleotide polymorphisms (SNPs) of CYP enzymes on the efficacy of autologous hematopoietic cell transplantation (HCT) for lymphoma. SNP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Blood Marrow Transplant
Prif Awduron: Bachanova, Veronika, Shanley, Ryan, Malik, Farhana, Chauhan, Lata, Lamba, Vishal, Weisdorf, Daniel J., Burns, Linda J., Lamba, Jatinder Kaur
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772424/
https://ncbi.nlm.nih.gov/pubmed/25677220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.02.001
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