Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-containing Conditioning and Autologous Transplantation for Lymphoma

Cyclophosphamide (Cy) is a prodrug that depends on bioactivation by hepatic cytochrome P450 (CYP) enzymes for its cytotoxicity. We evaluated the influence of single nucleotide polymorphisms (SNPs) of CYP enzymes on the efficacy of autologous hematopoietic cell transplantation (HCT) for lymphoma. SNP...

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Detaylı Bibliyografya
Yayımlandı:Biol Blood Marrow Transplant
Asıl Yazarlar: Bachanova, Veronika, Shanley, Ryan, Malik, Farhana, Chauhan, Lata, Lamba, Vishal, Weisdorf, Daniel J., Burns, Linda J., Lamba, Jatinder Kaur
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772424/
https://ncbi.nlm.nih.gov/pubmed/25677220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.02.001
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