Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients

BACKGROUND: Neuroinflammation is increasingly recognized as contributing to the pathogenesis of depression. Key inflammatory markers as well as kynurenic acid (KYNA) and quinolinic acid (QUIN), both tryptophan metabolites, have been associated with depressive symptoms and suicidality. The aim of the...

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Publicat a:J Neuroinflammation
Autors principals: Schwieler, Lilly, Samuelsson, Martin, Frye, Mark A., Bhat, Maria, Schuppe-Koistinen, Ina, Jungholm, Oscar, Johansson, Anette G., Landén, Mikael, Sellgren, Carl M., Erhardt, Sophie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772340/
https://ncbi.nlm.nih.gov/pubmed/26925576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0517-7
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