Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients

BACKGROUND: Neuroinflammation is increasingly recognized as contributing to the pathogenesis of depression. Key inflammatory markers as well as kynurenic acid (KYNA) and quinolinic acid (QUIN), both tryptophan metabolites, have been associated with depressive symptoms and suicidality. The aim of the...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Schwieler, Lilly, Samuelsson, Martin, Frye, Mark A., Bhat, Maria, Schuppe-Koistinen, Ina, Jungholm, Oscar, Johansson, Anette G., Landén, Mikael, Sellgren, Carl M., Erhardt, Sophie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772340/
https://ncbi.nlm.nih.gov/pubmed/26925576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0517-7
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