Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients

BACKGROUND: Neuroinflammation is increasingly recognized as contributing to the pathogenesis of depression. Key inflammatory markers as well as kynurenic acid (KYNA) and quinolinic acid (QUIN), both tryptophan metabolites, have been associated with depressive symptoms and suicidality. The aim of the...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Schwieler, Lilly, Samuelsson, Martin, Frye, Mark A., Bhat, Maria, Schuppe-Koistinen, Ina, Jungholm, Oscar, Johansson, Anette G., Landén, Mikael, Sellgren, Carl M., Erhardt, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772340/
https://ncbi.nlm.nih.gov/pubmed/26925576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0517-7
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