Prefrontal microRNA-221 Mediates Environmental Enrichment-Induced Increase of Locomotor Sensitivity to Nicotine

BACKGROUND: Environmental enrichment alters susceptibility in developing drug addiction. We have demonstrated that rats raised in an enriched condition are more sensitive than rats raised in an impoverished condition to nicotine-induced locomotor activity, and this is associated with alterations of...

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Pubblicato in:Int J Neuropsychopharmacol
Autori principali: Gomez, Adrian M., Altomare, Diego, Sun, Wei-Lun, Midde, Narasimha M., Ji, Hao, Shtutman, Michael, Turner, Jill R., Creek, Kim E., Zhu, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772274/
https://ncbi.nlm.nih.gov/pubmed/26232787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv090
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