Intra-ventral tegmental area HIV-1 Tat(1–86) attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats

Cigarette smoking prevalence in the HIV-positive individuals is profoundly higher than that in the HIV-negative individuals. We have demonstrated that HIV-1 transgenic rats exhibit attenuated nicotine-mediated locomotor activity, altered cAMP response element binding protein (CREB) and extracellular...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Zhu, Jun, Midde, Narasimha M., Gomez, Adrian M., Sun, Wei-Lun, Harrod, Steven B.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473058/
https://ncbi.nlm.nih.gov/pubmed/26150803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00540
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