Blockade of Glioma Proliferation Through Allosteric Inhibition of JAK2

The gene that encodes the epidermal growth factor receptor (EGFR) is frequently overexpressed or mutated in human cancers, including glioblastoma. However, the efficacy of EGFR-targeted small-molecule inhibitors or monoclonal antibodies in glioblastomas that also have mutation or deletion of the gen...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Signal
मुख्य लेखकों: He, Kunyan, Qi, Qi, Chan, Chi-Bun, Xiao, Ge, Liu, Xia, Tucker-Burden, Carol, Wang, Liya, Mao, Hui, Lu, Xiang, McDonald, Frank E., Luo, Hongbo, Fan, Qi-Wen, Weiss, William A., Sun, Shi-Yong, Brat, Daniel J., Ye, Keqiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772155/
https://ncbi.nlm.nih.gov/pubmed/23838182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003900
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