Blockade of Glioma Proliferation Through Allosteric Inhibition of JAK2

The gene that encodes the epidermal growth factor receptor (EGFR) is frequently overexpressed or mutated in human cancers, including glioblastoma. However, the efficacy of EGFR-targeted small-molecule inhibitors or monoclonal antibodies in glioblastomas that also have mutation or deletion of the gen...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: He, Kunyan, Qi, Qi, Chan, Chi-Bun, Xiao, Ge, Liu, Xia, Tucker-Burden, Carol, Wang, Liya, Mao, Hui, Lu, Xiang, McDonald, Frank E., Luo, Hongbo, Fan, Qi-Wen, Weiss, William A., Sun, Shi-Yong, Brat, Daniel J., Ye, Keqiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772155/
https://ncbi.nlm.nih.gov/pubmed/23838182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003900
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