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Determination of mRNA fate by different RNA polymerase II promoters.

Translational stop mutations of the human beta-globin gene cause a reduction of cytoplasmic mRNA accumulation in thalassemia patients and in transfection models. The exact mechanism underlying this phenomenon has remained enigmatic but is known to be post-transcriptional. We have used transfected He...

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Détails bibliographiques
Auteurs principaux: Enssle, J, Kugler, W, Hentze, M W, Kulozik, A E
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC47719/
https://ncbi.nlm.nih.gov/pubmed/8234261
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