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Determination of mRNA fate by different RNA polymerase II promoters.

Translational stop mutations of the human beta-globin gene cause a reduction of cytoplasmic mRNA accumulation in thalassemia patients and in transfection models. The exact mechanism underlying this phenomenon has remained enigmatic but is known to be post-transcriptional. We have used transfected He...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Enssle, J, Kugler, W, Hentze, M W, Kulozik, A E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47719/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234261/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10091
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