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The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane
Bardet-Biedl syndrome (BBS) is a highly pleiotropic autosomal recessive disorder associated with a wide range of phenotypes including obesity. However, the underlying mechanism remains unclear. Here, we show that neuronal BBSome is a critical determinant of energy balance through its role in the reg...
محفوظ في:
| الحاوية / القاعدة: | PLoS Genet |
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| المؤلفون الرئيسيون: | , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science
2016
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4771807/ https://ncbi.nlm.nih.gov/pubmed/26926121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005890 |
| الوسوم: |
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