Characterizing monkeypox virus specific CD8+ T cell epitopes in rhesus macaques

To characterize T cell epitopes in monkeypox virus (MPXV) infected rhesus macaques, we utilized IFNγ Elispot assay to screen 400 predicted peptides from 20 MPXV proteins. Two peptides from the F8L protein, an analog of E9L protein in vaccinia, were found to elicit CD8+ T cell responses. Prediction a...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: Song, Haifeng, Sidney, John, Wiseman, Roger W, Josleyn, Nicole, Cohen, Melanie, Blaney, Joseph E, Jahrling, Peter B, Sette, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. Published by Elsevier Inc. 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771384/
https://ncbi.nlm.nih.gov/pubmed/24210113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.09.003
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