Characterizing monkeypox virus specific CD8+ T cell epitopes in rhesus macaques

To characterize T cell epitopes in monkeypox virus (MPXV) infected rhesus macaques, we utilized IFNγ Elispot assay to screen 400 predicted peptides from 20 MPXV proteins. Two peptides from the F8L protein, an analog of E9L protein in vaccinia, were found to elicit CD8+ T cell responses. Prediction a...

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Publicado no:Virology
Main Authors: Song, Haifeng, Sidney, John, Wiseman, Roger W, Josleyn, Nicole, Cohen, Melanie, Blaney, Joseph E, Jahrling, Peter B, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. Published by Elsevier Inc. 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771384/
https://ncbi.nlm.nih.gov/pubmed/24210113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.09.003
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