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The Variable Region of Pneumococcal Pathogenicity Island 1 Is Responsible for Unusually High Virulence of a Serotype 1 Isolate

Streptococcus pneumoniae is the leading infectious cause of death in children in the world. However, the mechanisms that drive the progression from asymptomatic colonization to disease are poorly understood. Two virulence-associated genomic accessory regions (ARs) were deleted in a highly virulent s...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Harvey, Richard M., Trappetti, Claudia, Mahdi, Layla K., Wang, Hui, McAllister, Lauren J., Scalvini, Alexandra, Paton, Adrienne W., Paton, James C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771350/
https://ncbi.nlm.nih.gov/pubmed/26755156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01454-15
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