The Variable Region of Pneumococcal Pathogenicity Island 1 Is Responsible for Unusually High Virulence of a Serotype 1 Isolate

Streptococcus pneumoniae is the leading infectious cause of death in children in the world. However, the mechanisms that drive the progression from asymptomatic colonization to disease are poorly understood. Two virulence-associated genomic accessory regions (ARs) were deleted in a highly virulent s...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Infect Immun
Κύριοι συγγραφείς: Harvey, Richard M., Trappetti, Claudia, Mahdi, Layla K., Wang, Hui, McAllister, Lauren J., Scalvini, Alexandra, Paton, Adrienne W., Paton, James C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2016
Θέματα:
Bacterial Infections
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771350/
https://ncbi.nlm.nih.gov/pubmed/26755156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01454-15
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