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The Variable Region of Pneumococcal Pathogenicity Island 1 Is Responsible for Unusually High Virulence of a Serotype 1 Isolate

Streptococcus pneumoniae is the leading infectious cause of death in children in the world. However, the mechanisms that drive the progression from asymptomatic colonization to disease are poorly understood. Two virulence-associated genomic accessory regions (ARs) were deleted in a highly virulent s...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Harvey, Richard M., Trappetti, Claudia, Mahdi, Layla K., Wang, Hui, McAllister, Lauren J., Scalvini, Alexandra, Paton, Adrienne W., Paton, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771350/
https://ncbi.nlm.nih.gov/pubmed/26755156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01454-15
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