The Variable Region of Pneumococcal Pathogenicity Island 1 Is Responsible for Unusually High Virulence of a Serotype 1 Isolate

Streptococcus pneumoniae is the leading infectious cause of death in children in the world. However, the mechanisms that drive the progression from asymptomatic colonization to disease are poorly understood. Two virulence-associated genomic accessory regions (ARs) were deleted in a highly virulent s...

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Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Harvey, Richard M., Trappetti, Claudia, Mahdi, Layla K., Wang, Hui, McAllister, Lauren J., Scalvini, Alexandra, Paton, Adrienne W., Paton, James C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Bacterial Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771350/
https://ncbi.nlm.nih.gov/pubmed/26755156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01454-15
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