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The Variable Region of Pneumococcal Pathogenicity Island 1 Is Responsible for Unusually High Virulence of a Serotype 1 Isolate

Streptococcus pneumoniae is the leading infectious cause of death in children in the world. However, the mechanisms that drive the progression from asymptomatic colonization to disease are poorly understood. Two virulence-associated genomic accessory regions (ARs) were deleted in a highly virulent s...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Infect Immun
Main Authors: Harvey, Richard M., Trappetti, Claudia, Mahdi, Layla K., Wang, Hui, McAllister, Lauren J., Scalvini, Alexandra, Paton, Adrienne W., Paton, James C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771350/
https://ncbi.nlm.nih.gov/pubmed/26755156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01454-15
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