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Identification of the β-catenin/JNK/prothymosin-alpha axis as a novel target of sorafenib in hepatocellular carcinoma cells

Sorafenib is a kinase inhibitor used as anticancer drug against various human tumors, including advanced hepatocellular carcinoma (HCC). β-Catenin and prothymosin alpha (PTMA) are overexpressed in HCC and other tumors. Previous studies have shown that PTMA expression modulates the response of HCC ce...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Lin, Yi-Te, Chao, Chuck C.-K.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770752/
https://ncbi.nlm.nih.gov/pubmed/26517516
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