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Glutamine synthetase mediates sorafenib sensitivity in β-catenin-active hepatocellular carcinoma cells

The gene encoding β-catenin is frequently mutated in hepatocellular carcinoma cells. While the oncogenicity of β-catenin has been extensively studied, β-catenin’s role in hepatocellular carcinoma tumor metabolism is currently less well understood. In this study, we found that β-catenin regulates the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Mol Med
Hauptverfasser: Sohn, Bo Hwa, Park, In Young, Shin, Ji-Hyun, Yim, Sun Young, Lee, Ju-Seog
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992988/
https://ncbi.nlm.nih.gov/pubmed/29303508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.174
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