Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3β pathway in human colon cancer

Hes1 is a transcription factor that influences cell proliferation and differentiation. However, the effect of Hes1 on invasiveness and the underlying mechanism remain unknown. In the current study, we found that Hes1 suppressed cell apoptosis, promoted cell growth, induced EMT phenotype and cytoskel...

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Vydáno v:Oncotarget
Hlavní autoři: Gao, Fei, Huang, Wei, Zhang, YuQin, Tang, ShaoHui, Zheng, Lin, Ma, Feng, Wang, YiMing, Tang, Hui, Li, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770728/
https://ncbi.nlm.nih.gov/pubmed/26452029
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