Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3β pathway in human colon cancer

Hes1 is a transcription factor that influences cell proliferation and differentiation. However, the effect of Hes1 on invasiveness and the underlying mechanism remain unknown. In the current study, we found that Hes1 suppressed cell apoptosis, promoted cell growth, induced EMT phenotype and cytoskel...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gao, Fei, Huang, Wei, Zhang, YuQin, Tang, ShaoHui, Zheng, Lin, Ma, Feng, Wang, YiMing, Tang, Hui, Li, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770728/
https://ncbi.nlm.nih.gov/pubmed/26452029
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