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CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo

MicroRNAs are small and non-coding RNA molecules with the master role in regulation of gene expression at post-transcriptional/translational levels. Many methods have been developed for microRNA loss-of-function study, such as antisense inhibitors and sponges; however, the robustness, specificity, a...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Chang, Hong, Yi, Bin, Ma, Ruixia, Zhang, Xiaoguo, Zhao, Hongyou, Xi, Yaguang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770416/
https://ncbi.nlm.nih.gov/pubmed/26924382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22312
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