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CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo
MicroRNAs are small and non-coding RNA molecules with the master role in regulation of gene expression at post-transcriptional/translational levels. Many methods have been developed for microRNA loss-of-function study, such as antisense inhibitors and sponges; however, the robustness, specificity, a...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770416/ https://ncbi.nlm.nih.gov/pubmed/26924382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22312 |
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