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CRISPR/Cas9-Mediated Gene Knock-Down in Post-Mitotic Neurons
The prokaryotic adaptive immune system CRISPR/Cas9 has recently been adapted for genome editing in eukaryotic cells. This technique allows for sequence-specific induction of double-strand breaks in genomic DNA of individual cells, effectively resulting in knock-out of targeted genes. It thus promise...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139396/ https://ncbi.nlm.nih.gov/pubmed/25140704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105584 |
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