V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

BACKGROUND: Highly potent broadly neutralizing monoclonal antibodies (bNAbs) have been obtained from individuals infected by HIV-1 group M variants. We analyzed the cross-group neutralization potency of these bNAbs toward non-M primary isolates (PI). MATERIAL AND METHODS: The sensitivity to neutrali...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Morgand, Marion, Bouvin-Pley, Mélanie, Plantier, Jean-Christophe, Moreau, Alain, Alessandri, Elodie, Simon, François, Pace, Craig S., Pancera, Marie, Ho, David D., Poignard, Pascal, Bjorkman, Pamela J., Mouquet, Hugo, Nussenzweig, Michel C., Kwong, Peter D., Baty, Daniel, Chames, Patrick, Braibant, Martine, Barin, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Assuntos:
Basic and Translational Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770367/
https://ncbi.nlm.nih.gov/pubmed/26413851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000854
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