Evidence for a Continuous Drift of the HIV-1 Species towards Higher Resistance to Neutralizing Antibodies over the Course of the Epidemic

We compared the neutralization sensitivity of early/transmitted HIV-1 variants from patients infected by subtype B viruses at 3 periods of the epidemic (1987–1991, 1996–2000, 2006–2010). Infectious pseudotyped viruses expressing envelope glycoproteins representative of the viral quasi-species infect...

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Main Authors: Bouvin-Pley, Mélanie, Morgand, Marion, Moreau, Alain, Jestin, Pauline, Simonnet, Claire, Tran, Laurent, Goujard, Cécile, Meyer, Laurence, Barin, Francis, Braibant, Martine
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701719/
https://ncbi.nlm.nih.gov/pubmed/23853594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003477
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