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Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes
OBJECTIVE: Although glucagon-secreting α-cells and insulin-secreting β-cells have opposing functions in regulating plasma glucose levels, the two cell types share a common developmental origin and exhibit overlapping transcriptomes and epigenomes. Notably, destruction of β-cells can stimulate repopu...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770267/ https://ncbi.nlm.nih.gov/pubmed/26977395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.01.002 |
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