Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis

Regulation of hematopoiesis during human development remains poorly defined. Here we applied single-cell RNA sequencing (scRNA-seq) and single-cell assay for transposase-accessible chromatin sequencing (scATAC-seq) to over 8,000 human immunophenotypic blood cells from fetal liver and bone marrow. We...

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Udgivet i:Cell Stem Cell
Main Authors: Ranzoni, Anna Maria, Tangherloni, Andrea, Berest, Ivan, Riva, Simone Giovanni, Myers, Brynelle, Strzelecka, Paulina M., Xu, Jiarui, Panada, Elisa, Mohorianu, Irina, Zaugg, Judith B., Cvejic, Ana
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939551/
https://ncbi.nlm.nih.gov/pubmed/33352111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.11.015
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