“Receptor protein tyrosine phosphatase alpha enhances rheumatoid synovial fibroblast signaling and promotes arthritis in mice”

OBJECTIVE: During rheumatoid arthritis (RA), fibroblast-like synoviocytes (FLS) critically promote disease pathogenesis by aggressively invading the joint extracellular matrix. The focal adhesion kinase (FAK) signaling pathway is emerging as a contributor to RA FLS anomalous behavior. The receptor p...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Stanford, Stephanie M., Svensson, Mattias N. D., Sacchetti, Cristiano, Pilo, Caila A., Wu, Dennis J., Kiosses, William B., Hellvard, Annelie, Bergum, Brith, Aleman Muench, German R., Elly, Christian, Liu, Yun-Cai, den Hertog, Jeroen, Elson, Ari, Sap, Jan, Mydel, Piotr, Boyle, David L., Corr, Maripat, Firestein, Gary S., Bottini, Nunzio
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770259/
https://ncbi.nlm.nih.gov/pubmed/26414708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39442
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