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Effects of tRNA modification on translational accuracy depend on intrinsic codon–anticodon strength
Cellular health and growth requires protein synthesis to be both efficient to ensure sufficient production, and accurate to avoid producing defective or unstable proteins. The background of misreading error frequency by individual tRNAs is as low as 2 × 10(−6) per codon but is codon-specific with so...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770228/ https://ncbi.nlm.nih.gov/pubmed/26704976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1506 |
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