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Nucleotide modifications and tRNA anticodon–mRNA codon interactions on the ribosome
We have carried out molecular dynamics simulations of the tRNA anticodon and mRNA codon, inside the ribosome, to study the effect of the common tRNA modifications cmo(5)U34 and m(6)A37. In tRNA(Val), these modifications allow all four nucleotides to be successfully read at the wobble position in a c...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222130/ https://ncbi.nlm.nih.gov/pubmed/22028366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.029231.111 |
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