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Nucleotide modifications and tRNA anticodon–mRNA codon interactions on the ribosome

We have carried out molecular dynamics simulations of the tRNA anticodon and mRNA codon, inside the ribosome, to study the effect of the common tRNA modifications cmo(5)U34 and m(6)A37. In tRNA(Val), these modifications allow all four nucleotides to be successfully read at the wobble position in a c...

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Main Authors: Allnér, Olof, Nilsson, Lennart
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222130/
https://ncbi.nlm.nih.gov/pubmed/22028366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.029231.111
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