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Nucleotide modifications and tRNA anticodon–mRNA codon interactions on the ribosome

We have carried out molecular dynamics simulations of the tRNA anticodon and mRNA codon, inside the ribosome, to study the effect of the common tRNA modifications cmo(5)U34 and m(6)A37. In tRNA(Val), these modifications allow all four nucleotides to be successfully read at the wobble position in a c...

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Detalles Bibliográficos
Main Authors: Allnér, Olof, Nilsson, Lennart
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222130/
https://ncbi.nlm.nih.gov/pubmed/22028366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.029231.111
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