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Using the mouse to model human disease: increasing validity and reproducibility

Experiments that use the mouse as a model for disease have recently come under scrutiny because of the repeated failure of data, particularly derived from preclinical studies, to be replicated or translated to humans. The usefulness of mouse models has been questioned because of irreproducibility an...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Justice, Monica J., Dhillon, Paraminder
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770152/
https://ncbi.nlm.nih.gov/pubmed/26839397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.024547
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