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Using the mouse to model human disease: increasing validity and reproducibility

Experiments that use the mouse as a model for disease have recently come under scrutiny because of the repeated failure of data, particularly derived from preclinical studies, to be replicated or translated to humans. The usefulness of mouse models has been questioned because of irreproducibility an...

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Détails bibliographiques
Publié dans:Dis Model Mech
Auteurs principaux: Justice, Monica J., Dhillon, Paraminder
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770152/
https://ncbi.nlm.nih.gov/pubmed/26839397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.024547
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