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Technical approaches for mouse models of human disease

The mouse is the leading organism for disease research. A rich resource of genetic variation occurs naturally in inbred and special strains owing to spontaneous mutations. However, one can also obtain desired gene mutations by using the following processes: targeted mutations that eliminate function...

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Detalhes bibliográficos
Main Authors: Justice, Monica J., Siracusa, Linda D., Stewart, A. Francis
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097452/
https://ncbi.nlm.nih.gov/pubmed/21558063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.000901
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