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Humanized Mouse Models to Study Human Diseases

PURPOSE OF REVIEW: Update on humanized mouse models and their use in biomedical research. RECENT FINDINGS: The recent description of immunodeficient mice bearing a mutated IL-2 receptor gamma chain (IL2ry) facilitated greatly the engraftment and function of human hematolymphoid cells and other cells...

詳細記述

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書誌詳細
主要な著者: Brehm, Michael A., Shultz, Leonard D., Greiner, Dale L.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892284/
https://ncbi.nlm.nih.gov/pubmed/20150806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MED.0b013e328337282f
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