Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen

Targeted cell- or region-specific gene recombination is widely used in the functional analysis of genes implicated in development and disease. In the brain, targeted gene recombination has become a mainstream approach to study neurodegeneration or tumorigenesis. The use of the Cre-loxP system to stu...

Full description

Saved in:
Bibliographic Details
Published in:Dis Model Mech
Main Authors: Benedykcinska, Anna, Ferreira, Andreia, Lau, Joanne, Broni, Jessica, Richard-Loendt, Angela, Henriquez, Nico V., Brandner, Sebastian
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2016
Subjects:
Resource Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770146/
https://ncbi.nlm.nih.gov/pubmed/26704996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.022715
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items