In Vivo Performance and Properties of Tamoxifen Metabolites for CreERT2 Control

Mutant Estrogen Receptor (ERT2) ligand-binding domain fusions with Cre recombinase are a key tool for spatio-temporally controlled genetic recombination with the Cre/lox system. CreERT2 is efficiently activated in a concentration-dependent manner by the Tamoxifen metabolite trans-4-OH-Tamoxifen (tra...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Felker, Anastasia, Nieuwenhuize, Susan, Dolbois, Aymeric, Blazkova, Kristyna, Hess, Christopher, Low, Larry W. L., Burger, Sibylle, Samson, Natasha, Carney, Tom J., Bartunek, Petr, Nevado, Cristina, Mosimann, Christian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831813/
https://ncbi.nlm.nih.gov/pubmed/27077909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152989
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