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NOVEL APPROACH TO MODEL BRAIN TUMOURS BY INDUCING LOCALLY RESTRICTED AND STEM CELL SELECTIVE GENE TARGETING
BACKGROUND: A key challenge in determining the cellular origin of brain tumours is the identification and selective targeting of a biological relevant stem and progenitor population. Established approaches use cre mediated recombination of tumour suppressor genes, using constitutively expressed, ind...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144490/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.25 |
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