NOVEL APPROACH TO MODEL BRAIN TUMOURS BY INDUCING LOCALLY RESTRICTED AND STEM CELL SELECTIVE GENE TARGETING

BACKGROUND: A key challenge in determining the cellular origin of brain tumours is the identification and selective targeting of a biological relevant stem and progenitor population. Established approaches use cre mediated recombination of tumour suppressor genes, using constitutively expressed, ind...

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Hauptverfasser: Brandner, Sebastian, Benedykcinska, Anna, Li, Ning, Henriquez, Nick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144490/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.25
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