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Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes

It has been suggested that intrinsic brain tumours originate from a neural stem/progenitor cell population in the subventricular zone of the post-natal brain. However, the influence of the initial genetic mutation on the phenotype as well as the contribution of mature astrocytes to the formation of...

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Autors principals: Jacques, Thomas S, Swales, Alexander, Brzozowski, Monika J, Henriquez, Nico V, Linehan, Jacqueline M, Mirzadeh, Zaman, O' Malley, Catherine, Naumann, Heike, Alvarez-Buylla, Arturo, Brandner, Sebastian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808375/
https://ncbi.nlm.nih.gov/pubmed/19927122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.327
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