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CRM1 inhibitor S109 suppresses cell proliferation and induces cell cycle arrest in renal cancer cells
Abnormal localization of tumor suppressor proteins is a common feature of renal cancer. Nuclear export of these tumor suppressor proteins is mediated by chromosome region maintenance-1 (CRM1). Here, we investigated the antitumor eff ects of a novel reversible inhibitor of CRM1 on renal cancer cells....
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| Publicado no: | Korean J Physiol Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Physiological Society and The Korean Society of Pharmacology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770106/ https://ncbi.nlm.nih.gov/pubmed/26937212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.2.161 |
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