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Novel reversible selective inhibitor of nuclear export shows that CRM1 is a target in colorectal cancer cells

Colorectal cancer arises via a multistep carcinogenic process and the deregulation of multiple pathways. Thus, the simultaneous targeting of multiple pathways may be a promising therapeutic approach for colorectal treatment. CRM1 is an attractive cancer drug target, because it can regulate multiple...

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Publicat a:Cancer Biol Ther
Autors principals: Niu, Mingshan, Chong, Yulong, Han, Yan, Liu, Xuejiao
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622914/
https://ncbi.nlm.nih.gov/pubmed/25996664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1047569
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