CRM1 inhibitor S109 suppresses cell proliferation and induces cell cycle arrest in renal cancer cells

Abnormal localization of tumor suppressor proteins is a common feature of renal cancer. Nuclear export of these tumor suppressor proteins is mediated by chromosome region maintenance-1 (CRM1). Here, we investigated the antitumor eff ects of a novel reversible inhibitor of CRM1 on renal cancer cells....

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Vydáno v:Korean J Physiol Pharmacol
Hlavní autoři: Liu, Xuejiao, Chong, Yulong, Liu, Huize, Han, Yan, Niu, Mingshan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770106/
https://ncbi.nlm.nih.gov/pubmed/26937212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.2.161
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