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Targeted alignment and end repair elimination increase alignment and methylation measure accuracy for reduced representation bisulfite sequencing data
BACKGROUND: DNA methylation is an important epigenetic modification involved in many biological processes. Reduced representation bisulfite sequencing (RRBS) is a cost-effective method for studying DNA methylation at single base resolution. Although several tools are available for RRBS data processi...
Shranjeno v:
| izdano v: | BMC Genomics |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769831/ https://ncbi.nlm.nih.gov/pubmed/26922377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2494-8 |
| Oznake: |
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