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Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1
BACKGROUND: Although the prolonged use of rapamycin may cause unwanted side effects such as hyperlipidemia, the underlying mechanism remains unknown. Prox1 is a transcription factor responsible for the development of several tissues including lymphatics and liver. There is growing evidences that Pro...
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| Publié dans: | Lipids Health Dis |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769820/ https://ncbi.nlm.nih.gov/pubmed/26922671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-016-0211-x |
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