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Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1
BACKGROUND: Although the prolonged use of rapamycin may cause unwanted side effects such as hyperlipidemia, the underlying mechanism remains unknown. Prox1 is a transcription factor responsible for the development of several tissues including lymphatics and liver. There is growing evidences that Pro...
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Publicado no: | Lipids Health Dis |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769820/ https://ncbi.nlm.nih.gov/pubmed/26922671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-016-0211-x |
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