Cerebroprotection of Flavanol (−)-Epicatechin after Traumatic Brain Injury via Nrf2-dependent and –independent Pathways

Traumatic brain injury (TBI), which leads to disability, dysfunction, and even death, is a prominent health problem worldwide with no effective treatment. A brain-permeable flavonoid named (−)-epicatechin (EC) modulates redox/oxidative stress and has been shown to be beneficial for vascular and cogn...

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Pubblicato in:Free Radic Biol Med
Autori principali: Cheng, Tian, Wang, Wenzhu, Li, Qian, Han, Xiaoning, Xing, Jing, Qi, Cunfang, Lan, Xi, Wan, Jieru, Potts, Alexa, Guan, Fangxia, Wang, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769660/
https://ncbi.nlm.nih.gov/pubmed/26724590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.12.027
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