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Corticosterone Blocks Ovarian Cyclicity and the LH Surge via Decreased Kisspeptin Neuron Activation in Female Mice

Stress elicits activation of the hypothalamic-pituitary-adrenal axis, which leads to enhanced circulating glucocorticoids, as well as impaired gonadotropin secretion and ovarian cyclicity. Here, we tested the hypothesis that elevated, stress-levels of glucocorticoids disrupt ovarian cyclicity by int...

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Publicat a:Endocrinology
Autors principals: Luo, Elena, Stephens, Shannon B. Z., Chaing, Sharon, Munaganuru, Nagambika, Kauffman, Alexander S., Breen, Kellie M.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769373/
https://ncbi.nlm.nih.gov/pubmed/26697722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1711
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